Bleeding heck......How much to transfuse??

Soon we will start recruiting patients with GI bleeding, as we become a centre for the HALT-IT trail (the use of tranexamic acid in GI bleed). Also in development are new evidence based guidelines for best current practice in treating difficult upper GI bleed patients. With this in mind here is an interesting paper looking at the use of transfusion in these patients..... It seems that we shouldn't just load them with all the blood products we can find......see what you think??


Transfusion strategies for Acute upper GI Bleed (N Engl J Med. 2013 Jan 3;368(1)